Essay --

bizarre genetic disease that seems to accelerate ageing could hold the key to longer lives for children with progeria.Progeria is an extremely rare, fatal genetic condition which causes babies to age quickly. Progeria was first described in an academic journal by Dr. Jonathan Hutchinson in 1886 and also by Dr. Hasting Gilford in 1897 both man was from England (Nordqvist 1). After discovering the two people they later came up with a new name for Progeria called Hutchinson-Gilford Progeria Syndrome (HGPS). Today in life there 53 cases of Progeria around the world and only 2 in the UK.1 in every 4 to 8 million babies are born with Progeria. Progeria effect all race equal boys and girls. As newborn, children with Progeria usually appear normal at birth. However, within a year their growth rate slows and they soon are much smaller and weigh less than other children they age. Then later they begin to accelerate aging and some signs of progeria may start. Growth failure, Loss of body, Loss of hair, Skin starts to look aged, Stiffness in the joint, Hip dislocation, Generalized atherosclerosis, and stroke are all symptoms that child with Progeria will have. Children who suffer from Progeria are genetically susceptible to premature, progressive heart disease (Davis 2). Progeria appears to occur without cause and it is not seen in siblings of affected children. Children with Progeria have a surprisingly appearance. 90% of children with Progeria have a mutation on the gene that encodes Lamin A, a protein that holds the nucleus of the cell together (Conley 4). Lamin A protein makes the nucleus stable it leads to the process of premature aging among Progeria patients. Experts do not believe that Progeria is hereditary. In about 1 in ev... ...yday because you they never know when they might lose them. Progeria is not usually passed down in family. Children with Progeria often suffer from symptoms typically seen in elderly people (Davis1). People inherit the disease only one copy of the LMNA gene is enough to cause the disease because it is an autosomal dominant gene. The Progeria Research Foundation was created in 1999. Progeria does have parallels with normal ageing; at least in one key aspect how out blood vessels deteriorate. Researchers found that a drug known as rapamyein slowed and even stopped the disease progression the cells. Progeria only affected newborn babies. Progeria is a very rare disease that no one knows where it comes from. Research today is still haven’t come up with a way to stop the cure for Progeria. Some research found a way to make Progeria patients live longer then the age 13.

Washing and Constant Cleaning, an Obsessive-compulsive Disorder (OCD) E

Washing and Constant Cleaning, an Obsessive-compulsive Disorder (OCD) Abstract Washing and constant cleaning, an obsessive-compulsive disorder (OCD). OCD often goes undiagnosed. Patients obsessively wash, check something or hoard things to relieve themselves of an overwhelming anxiety, and are fully aware their behavior is abnormal. This research studies a 23-year-old married woman who sought treatment for a severe washing and cleaning problem and how the patient was treated. I will discuss how the patient was diagnosed, and treated with a form of cognitive behavioral psychotherapy or CBT (exposure and response treatment) and what medications can be used for treatment. Vickie, a 23 year-old married woman arrived with the company of her husband. Vickie had a problem with severe had washing and cleaning. She would wash her hands up to 30 times a day for at least 5 minutes each time. She always had the feeling that her hands were not really clean, she might touch the side of the sink after she rinsed her hands and then think they were dirty again. She also took two showers a day for up to 50 minutes or until all the hot water was gone. Other things she did to make herself feel clean is use alcohol to wipe things down that she would come into contact with, like her car seat before she set in it. She has been unable to seek employment as a Licensed Practical Nurse (LPN) due to her symptoms. I conducted four initial sessions, session one and two were to seek information about the history of her symptoms, obsessional content, including external and internal fears cues, beliefs about consequences, and information about passive avoidance patterns and types of rituals (Levenkron, 1991). I also requested Vickie before our next session to record all washing and cleaning that she did, including wiping things with alcohol. She recorded every time she washed, how long she washed, what made her wash, and how anxious she was before she washed. This kind of record will help us identify any sources of contamination she may have gotten and we can also use it to measure her progress during treatment; the third session was devoted to personal and family history; the fourth session was devoted to treatment planning. During the first three therapy sessions Vickie talked about her experiences of recurrent and persistent ideas, thought, impulses, ... ... to obtain anti-obsessional effects. Studies done to date suggest that the following dosages may be necessary: Luvox (up to 300 mg/day), Prozac (40-80 mg/day), Zoloft (up to 200 mg/day), Paxil (40-60 mg/day), Celexa (up to 60 mg/day), and Anafranil (up to 250 mg/day), (Jenike, 1999b). References American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author Engler, J. & Goleman, D. (1992). The authoritative guide for making informed choices about all types of psychotherapy. The Consumer’s Guide to Psychotherapy. New York, NY: Simon & Schuster/Fireside Levenkron, S. (1991). Treating & Understanding Crippling Habits. Obsessive-Compulsive Disorders. New York, NY: Warner Books. Jenike, J. (1999a). How to select a Behavior Therapist. Obsessive-Compulsive Foundation. Available: http://www.ocfoundation.org/ocf_0003.htm Jenike, J. (1999b). OCD medication: Adults. Obsessive-Compulsive Foundation. Retrieved November 18, 2001, from http://www.ocfoundation.org/ocf1050a.htm Obsessive-Compulsive Foundation: How is OCD treated. Retrieved November 14, 2001, from http://www.ocfoundation.org/ocf1030a.htm

Marketing Strategy and ECommerce :: GCSE Business Marketing BTEC Coursework

Marketing Strategy and ECommerce Introduction With the rapidly advancing technologies that are occurring in modern business, organisations are required to be ready, and able to adapt within their ever-changing environment. It is true across all diverse industries that in order to stay competitive, organisations must be able to utilise the various tools that technology has to offer. Technological factors have been of growing importance, particularly in recent years. A major factor involved in these technology issues is the use of the Internet as a major issue to modern organisations. The Internet has been rapidly growing since it's inception and is now commonly used in all sectors of societies, in all corners of the globe. The Internet has quickly become one of the most valuable assets in modern technology, and as such, is developing as an integral part of modern commerce. As with past technologies, the Internet will have future technological advances develop from its own growth. The task the organisations of in the new century? Realise future opportunities and threats, and base a strategy accordingly. "Is it clichà © to say that 'the Internet changes everything': the challenge now is to say what, how and how quickly". (When Companies Connect, 1999, p.19) The Internet has lead to the birth and evolution of electronic commerce or E-commerce. E-commerce has now become a key component of many organisations in the daily running of their business. Simply defined, "electronic commerce is a system of online shopping and information retrieval accessed through networks of personal computers". (Reedy, J. Schullo, S. Zimmerman, K. 2000, pg. 29) E-commerce challenges traditional organisational practices, and opens ups a vast array of issues that the organisations must address. By focusing on the varying levels of an organisation, it soon become apparent the effects that E-commerce can have. An understanding of the implication E-commerce has on such organisational divisions can help businesses gain understanding hence plan for it's inevitable continuing evolution. In terms of marketing, the modern organisation must be critically aware of the development of E-commerce, and the implications that it entails. "Marketers develop their own recipe of promotional tactics to fit the product lines or industries in which they compete. Now electronic communications tools are and will continue to be an important ingredient in the promotional mix" (Reedy, J. Schullo, S. Zimmerman, K. 2000, pg. 29) In assessing the implications of E-commerce in terms of marketing, it is important to understand its impact in respect to

How Life Was Growing Up Essay

Being the youngest sibling of three has always been hard on me. I was the only girl and growing up with my two brothers has always had its downfalls. I not only had to be around my brothers at all times, I was also surrounded by too many male cousins. Quite frankly, I can count how many female cousins I have in one hand. It is a real shame what a girl had to do just to be one of the guys. I was seven years old at the time and I still remember what happened like it was just yesterday. For the summer break my brothers and I along with our cousins stayed with our grandparents. My grandparents own acres and acres of land in the Philippines. Day by day we did nothing but run around the field, tackled each other, scared off the animals, and climbed trees. One summer day, we were playing tag and two of my cousins mentioned that they were getting bored. We then started playing truth or dare. Everything was going smoothly until I was dared to climb the highest tree my grandparents had. I was dared to climb the tree to picked fruits for everyone. Without thinking about it, I climbed the tree so fast with confidence I thought I was a super girl. However, what they did not know was I was scared of heights. I was trying my best to hide my fear, but as I looked down the ground, I started screaming for help. I watched my cousins along with my brothers laughed so hard few tears were coming down the side of their eyes. I then started crying out for help. Eventually one of my brothers came to my rescue. However as I was going down, one of my feet slipped. As I tried grabbing on to something for support, my life flashed before my eyes. As I was falling, nothing but grasp for air was the only sound you could hear. I fell onto the ground twelve feet high and fracture my forearm. It has been 18 years since the incident happened. Until this day, the memory of how I broke my arm still lives on through gathering with my families. As an adult, we still tend to make silly decision just to fit in. Whether it is done at work, around new people, around in-laws, and even around your own family, impressions are still a great deal for every single individual. No matter how young or old you may be, silly actions are bound to happen.

Is “Lord of the Flies” a Searching Examination

shiver got to have rules and obey them. After whole, were non savages were English. And the English argon best at everything. These are lines taken trot chapter 2 match the novel Lord tot the Flies. To show the change in the voice and the situation by the novel present is a nonher quote from the last chapter of the novel, l should have thought, said the officer as he visualized the search forwards him, l should have thought that a pack of British boys- youre in all British arent you? Could have been able to put up a erupt show than that taut. The novel shows Itself to be a plentitude of things, a comment on war, an post novel or d tilt of theatrical role reference. by the give-and-take decorate purport-beginnings to non just now warn us around the consequences of anformer(a)(prenominal) war, nevertheless excessively enables describe to view an array of different personalities and mess profiler Yes, Lord of the Flies is a searching scrutiny tot piece pe rsonality, where trot the contri only ifor non only gets an authorial ready on various fonts of people merely excessively get to, for themselves, form an motion picture of the individualistic of each and every char shamer.The moot protagonist of the novel is Ralph, a lucid and democratic leader who is Mathew obsessed with the fire. In the start of the novel he besides is Indifferent towards the easy target neandertal, only slowly learns to respect him. It Is Ralph who Initially keeps the boys think on their goal of being save. provided ads his mind gets clouded so does his objective. adorn shows Ralph to be the closed man, an evolved creature who conforms to comp either only still has his flaws.Ralph shows his flaws when he continues to edit away piggys asthma by adduceing Sucks to your as- marl whenever the affair is broached. He excessively shows poor supposition when he gives into his immemorial intellects and social functionicipates in the killing of Simon. Ralph to the lecturer symbolisms the leader who is civilized and commit plainly can often cutting and make mistakes. His relatable reactions and simple solutions represent a man of go away, vivo Is defeated by circumstance. He losss to let the fire continue but has in any case slight man position to do so, but still persists on determination a solution the next day.We also see him to be delusional at times, standardized when the blanket flickers In his header and he Is unable to think HIS biggest snatch of what can be called stupidly Is when he says, Supposing we go, looking like we used to, serve and hair brushed?- tater all we rent savages really and being preservationd isnt a game. He believes that patronage the savagery that has spread by means of varlet and this tribe they will listen to him if he takes a shower, it is possibly his biggest moment of failure. through the same instance we see some separate trait of homophile nature in him which Is desp eration.Ralph is trying to cling on to any little form of order and confide that he can muster. He go fors to come through the some other boys over with his ceaseeavourer to appeal to the little remnants of collocation, Another striking event that stands proscribed with respect to Ralph Is when he slaughters the beast, he Is the champion trying to establish decorum and It Is he who destroys the reason tort chaos. To contrasts Ralph as the civilized human being grace creates tinkers damn, the adversary. Ironically a choir boy, motherfucker slowly turns out to be overbearing dictator and comes to represent the evil or the ruthless side tot human nature.A first, dogshit goes along with Ralph and allows himself to be appeased as the head of the hunters. He is content with his position and desperately tries to gather meat. His first attempt at killing the animal is sinister not due to lack of skill, but because he still as some conscience remaining in him and is rattling s cared of committing the writ of execution. He also says that eyepatch he hunts he feels like he is being hunted. This shows the last fragments of earth left in him. He turns into an more or less repulsive animal at the end of the novel.Gilding shows mans primitive instincts in goof, his exigency for food, power and blood. We often wonder from where the deep seethed inkiness appears in Jack. I can only speculate that the intensive education provided to him in the church results in a catastrophic rebellion where Jack loses all backbone of sanity and informs to the baser human. Towards the end of the novel Jack is adhered to as the chief and everyone on the island businesss him. He hates piglet from the very beginning and is trepid of his intelligence.He knows that Piggys rationality could be responsible for his pin and could harm his dictatorship. He is envious of his higher(prenominal)-rankingity. His tone conveyed a warning, given out of the preen of ownership, and th e boys ate faster while there was still time. Jack establishes his authority through brutality and force. He symbolisms the savage and primitive opus of human nature. His interactions with others more or less result in a display of rage and anger and he pitilessly forces the others to adhere to him. He orders the murder of Simon, the theft of Piggys glasses and even asks for Rallys life.Gilding, through him examines, in depth the evil indoors man and the ugly part of the human mind. Another character that Gilding uses to kick upstairs examine the human race is that of Piggy. through this fat boy the author shows rationality, reason, science and intelligence. Piggy along with his specs is the symbol of light and provides an outlook into scientific man. Despite his intelligence, Piggy has his short comings he has asthma and is a social outcast due to his superior intellect. He is fear full of Jack and even says, We should fear each other.His character gives the reader yet anoth er example of a different type of human being, one who is above the shack intellectually but suffers from isolation and anxiety. Through him, Gilding dives deeper into the psyche of a visionary. spell Piggy, as a character does conduct himself to the examination of human nature, his finale too is a fair example of Gildings thesis. When Piggy is killed by the tone which is rolled buck we see no humanity left within these boys. We see only Ralph sorrow the loss of a great friend, but everybody else especially Jack is oblivious.This shows us the communal feeling of new within man. all told the boys were louses of Piggy, his glasses and his intelligence. The Conch too shatters with Piggy which and accentuates the dilapidation of civilization on the island, it also highlights mans complete disregard for rules and his natural instinct to rebel. If lack is part of darkest hues in the character palate, and Ralph can be painted in shades of grey, Simon resembles the purity of whit e. In Simon Gilding explores the spiritual and innately good part of the human heart.Simon thinks only for the good of all, he practices meditation and sacrifices himself in an endeavourer to save everybody. He is close to nature and is the only one who has a conversation with the sow. It is Simon, who understands the universal trueness that it is not each other that we should fear nor I it some third person, but it is the evil within us that will eventually USA . It is rather entourage at t TN this extraordinary, Christ-like texture is continually marginals and is at the end murdered unfeelingly. In him Gilding pictures the saint, the pure visionary who knows the truth.His character highlights the differently abele or the higher human nature, one which connects with God and Nature. With respect to Simon it is not only he who is a specimen to investigate human nature for Gilding, but his interactions with the sows head and his death too focus on some other human traits. For example when he negotiation to the sow he displays a curtain of bravery which could be taken as the bravery of a martyr or the fade of a coward. His death however, jibe to me displays the most range of human motions.The act itself shows primitive violence and carnal of necessity at its very roots. The reaction of the boys to the death is indifferent and they go on like nothing has happened, it shows that the different and often better people are always thrown and twisted away. It also shows the human habit of denial, where all the boys including Ralph completely deny any part in the killing. In the book, Simon is shown to be a true unsung martyr. The littlest in the book resemble the common man in society and his reflex reaction to conform, whereas the other biggies resemble the followers and ails of the leaders.A bugging who distinctly stands out is Roger, he acts as second in command to Jack and it is he who is responsible for Piggys death. All the boys fight for power, they all want to control something. The sow shows the need for security, the Conch the sciolistic need for rules and the glasses the human need for technology. Through the novel, Lord of the Flies Gilding not only dives into the human mind, heart and person by meaner of implication, but provides the reader with cover examples and instances where the various facets of human nature are displayed.It is ironic that when the beast is killed by Jack the fire begins to destroy, and it is the fire, not one of hope but one of destruction that leads to the rescue of the boys. Through all these examples from the text I can without a doubt say that the novel is truly a fine example of an in-depth analysis of human nature. It makes a powerful impact on the reader and gives them food for thought. It makes us think of not only the various possibilities but also the extent to which the human mind and its subjective evil nature can mug up a storm and leave a pile of destruction behind.

Primary research on motivation

needCourse ORGANISATIONAL BEHAVIOURFaculty band 2013-2016ClassTable OF Content Table OF field of studyS.NoSubjectPg. No.1.Student Declaration32.Introduction43.Questionnaire5-74.Analysis7-145.Decision15.Student DECLARATIONWe hereby declargon that any the members in our convention were present during the interview with Mr. Deepak Gupta, director of Thoro Packaging Industries Pvt. Ltd.. All the members pass all(prenominal) smudge actioned together on this initiate titled Motivation . Each of us had been assigned a pot of the entire undertaking and have contributed moderately to the consequence of this undertaking. The questionnaire prepared by us consists of inquiries that have conjointly been contributed by the members of our group. On the completion of this undertaking, we had acquired valuable apprehension and information pertaining to the motivational facet in the working of a private endeavor and the psychological predilection of its employees.IntroductionMotivationis amental characteristic that inspires an being to work on the desiredgoaland controls his behavior harmonizing to the demands. For illustration, Grades is a factor cause that allows us to analyze and work harder. It is an external or inborn force which compels us to execute an action to live up to a coveted end.Motivation helps the human to denigrate physical hurting and maximise pleasance and helps us derive assurance so that we can complete our end.QUESTIONNARIEI confide that the work that I do contributes to the ends of the organisation and makes a unlikeness.AlwaysSometimesRarelyNeverI readily take fraction voluntarily in meetings, treatments, arguments and supply suggestions that help crack our work.AlwaysSometimesRarelyNeverMy leader understands my strengths, endowments and abilities, and ensures that I get to use them on a fixedness footing.AlwaysSometimesRarelyNeverMy work is positively disputing. It stretches my abilities and possible, without coercing me into emp hasis.AlwaysSometimesRarelyNeverI intend that there is cracking cultural coherence surrounded by me and the organisation.AlwaysSometimesRarelyNeverThere are tinge chances for betterment and overall evolution in the organisation.AlwaysSometimesRarelyNeverI do non experience hesitating more or less showing my sentiments, predilections and positions, regardless of whether they are for or against an idea/proposition.AlwaysSometimesRarelyNeverI consider myself apprehended and valued by the organisation.AlwaysSometimesRarelyNeverMy sentiments are encouraged, want out, listened to and enacted upon.AlwaysSometimesRarelyNeverUnder-performance is analyzed, identified and rectified rapidly and efficaciously by the organisation.AlwaysSometimesRarelyNeverConflicts within the organisation are dealt with rapidly, efficaciously and in an just and indifferent mode.AlwaysSometimesRarelyNeverMy leader and I mutually decide upon marks on a unbendable footing, and I am clear most my ain ends that will assist me and the organisation buzz off successful.AlwaysSometimesRarelyNeverI believe that mypersonalends are just and am pipious either bit smashing as accomplishable and that I have a good opportunity of accomplishing them.AlwaysSometimesRarelyNeverI am good informed, clear and convinced some our team ends in the organisation.AlwaysSometimesRarelyNeverI am an of import and portion of my team contributing towards the accomplishment of the ends of the police team and organisation at big.AlwaysSometimesRarelyNeverI believe that oursquadends are just and ambitious all(prenominal) bit good as accomplishable and that I have a good opportunity of accomplishing them.AlwaysSometimesRarelyNeverMy squad places more importance on happening solutions and bettering everyday presentation, instead than interpersonal struggles, political relations, and unhealthy competition.AlwaysSometimesRarelyNeverThere is a sensible grade of trust between the concern and work force, and the higher-ups and subsidiaries of the organisation.AlwaysSometimesRarelyNeverI personally like working in the organisation and bask my work and the work environment.AlwaysSometimesRarelyNeverMy wage, clap benefits and blast benefits are sensible, just and equal.AlwaysSometimesRarelyNeverAnalysis1.I believe that the work that I do contributes to the ends of the organisation and makes a difference2.I readily take part voluntarily in meetings, treatments, arguments and supply suggestions that help better our work.3.My leader understands my strengths, endowments and abilities, and ensures that I get to use them on a regular footing.4.My work is positively disputing. It stretches my abilities and possible, without coercing me into emphasis.5.I believe that there is good cultural coherence between me and the organisation.6.There are equal chances for betterment and overall development in the organisation.7.I do non experience hesitating about showing my sentiments, ideas and positions , irrespective of whether they are for or against an idea/proposition.8.I consider myself appreciated and valued by the organisation9.My sentiments are encouraged, sought out, listened to and enacted upon.10.Under-performance is analyzed, identified and rectified rapidly and efficaciously by the organisation.11. Conflicts within the organisation are dealt with rapidly, efficaciously and in an just and indifferent mode.12.My leader and I reciprocally decide upon marks on a regular footing, and I am clear about my personal ends that will assist me and the organisation become successful.13.I believe that mypersonalends are just and ambitious every bit good as accomplishable and that I have a good opportunity of accomplishing them14.I am good informed, clear and convinced about our squad ends in the organisation15.I am an of import and portion of my squad contributing towards the accomplishment of the ends of the squad and organisation at big.16.I believe that oursquadends are just and ambitious every bit good as accomplishable and that I have a good opportunity of accomplishing them17.My squad places more importance on happening solutions and bettering universe presentation, instead than interpersonal struggles, political relations, and unhealthy competition.18.There is a sensible grade of trust between the committee and work force, and the higher-ups and subsidiaries of the organisation.19.I personally like working in the organisation and bask my work and the work environment.20.My wage, fringe benefits and fringe benefits are sensible, just and equal.DecisionThis undertaking was really exciting for all in our group as we got to teach a batch about motive with a field detonate to a private endeavor. We were able to derive a valuable penetration into the heads of the employees and their psychological feelings with regard to how move they felt within the administration. We ascertained the important contribution that motive dramas in any organisation, be it a private or a public endeavor. This is because motive is permeant in nature.We would wish to thank our Organisational deportment professor, Dr. Olive Nerulkar, for supplying us with an chance to larn about motive on the field through a questionnaire study of an organisations employees.pg. 1